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Updated: Aug 31, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
[Recurrent pregnancy loss: which immunological laboratory tests?]
G C Faure1, M C Béné, P Barbarino-Monnier
1Laboratoire d'immunologie, faculté de médecine de Nancy, BP 184, 54500 Vandoeuvre-les-Nancy, France. gilbert.faure@grip.u-nancy.fr
Abstract:
Recurrent unexplained abortions are defined as at least two successive abortions during the first trimester of pregnancy. Implication of autoimmunity processes is now widely recognized. The list of biological assays proposed in recurrent abortions is inspired from immunological exploration of systemic lupus erythematosus in which pregnancy usually induces high risk for the conception product. Other assays derive from immunological hypotheses explaining the tolerance paradox of pregnancy, but many have not yet been established and will still require clinical research protocols.
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