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Updated: Mar 28, 2026
Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
[Investigation on recurrent-associated gene expression pattern of recurrent-laryngeal squamous cell carcinoma]
Binquan Wang1, Yanqiu Chen, Shuxin Wen
1Department of Otorhinolaryngology, First Hospital of Shanxi Medical University, Taiyuan 030001.
Objective:
To screen out recurrent-associated gene in expression pattern of laryngeal squamous cell carcinoma(LSCC).
Method:
By cDNA array chip containing 18,000 gene, the gene expression pattern of cancer and normal mucosal tissues in 2 cases of LSCC, were compared and analyzed.
Result:
1. 218 genes expressed repeatedly and differentially in LSCC were discovery. Among these genes, up- and down-regulated were 137 and 81; 2. The genes whose expression difference was over 10 times were U02570, AW863712, AA523939 and NM_014381.
Conclusion:
The episode of recurrent LSCC was a process of disturbance of numerous gene expression. GTPase activating protein (U02570) and DNA mismatch repair gene(NM_014381) probably played a major role in the episode.
