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[Unilateral tonsillar enlargement and malignant tonsillar lymphoma]
Jianwei Qi1, Xianchao Fan, Changkuan Wang
1Department of Otolaryngology-Head and Neck Surgery,Affiliated Nanjing First Hospital of Nanjing Medical University,Nanjing 210006.
Summary
Unilateral tonsillar enlargement may indicate non-Hodgkin's lymphoma (NHL). Early diagnosis via tonsillectomy and histopathology, combined with chemotherapy and radiotherapy, offers a 60% 5-year survival rate for NHL patients.
Area of Science:
- Oncology
- Pathology
- Otorhinolaryngology
Context:
- Unilateral tonsillar enlargement is an uncommon presentation.
- Distinguishing benign from malignant causes is crucial for timely intervention.
Purpose:
- To identify clinical characteristics of malignant lymphoma in patients with unilateral tonsillar enlargement.
- To guide early diagnosis and treatment strategies.
Summary:
- This study analyzed 10 cases of non-Hodgkin's lymphoma (NHL) presenting with unilateral tonsillar enlargement.
- Patients underwent tonsillectomy, followed by chemotherapy in all cases and radiotherapy in 80% of cases.
- The 5-year survival rate was 60%.
Impact:
- Highlights the importance of considering malignant lymphoma in unilateral tonsillar enlargement.
- Emphasizes the role of histopathological examination for early detection.
- Suggests a combined treatment approach for improved patient outcomes.