Related Experiment Video
Updated: Aug 21, 2026
Facial Nerve Surgery in the Rat Model to Study Axonal Inhibition and Regeneration
Published on: May 5, 2020
[Changes of axoplasmic transportation during experimental facial nerve regeneration]
Hongmin Ma1, Jinling Wang, Jianhua Qiu
1Department of Otorhinolaryngology, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032.
Objective:
To determine the roles of axoplasmic transportation during regeneration after facial nerve injury.
Method:
Facial nucleus injection and isotopic-label tracer with liquid scintillation counting techniques were used to investigate the changes of radioactivity after guinea pig facial nerve compressed.
Result:
Axoplasmic transportation was observed again at 3 d after facial nerve injury, and the function recovered until 14 d. At 21 d after injury, it showed that transportation curve of radiolabeled protein was similar with that of the normal. There was particular curve in slow axoplasmic transportation that included two wave: W1 and W2. The axons regenerated at a rate of (2.84 +/- 0.12) mm/d in fast transportation while that of slow transportation is (3.16 +/- 0.08) mm/d.
Conclusion:
It suggests that axoplasmic transport act as a important role during the course of facial nerve regeneration.
