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Updated: Aug 15, 2026
Analysis of Pulmonary Dendritic Cell Maturation and Migration during Allergic Airway Inflammation
Published on: July 23, 2012
[Study of immunoregulation of dendritic cells in allergic rhinitis]
1Department of Otorhinolaryngology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Objective:
To investigate the immunoregulation of dendritic cells in allergic rhinitis.
Method:
Adopting the cell culture and the enzyme linked immunosorbant assay to examine the patients' Th1/Th2 in the blood. Observing that how is the DC's function in immunoregulation of allergic rhinitis.
Result:
The concentration of the IFN-gamma advanced obviously in post-stimulatory supernatant liquid after using the mature DC.
Conclusion:
The mature dendritic cells can polarize naive T-cells into Th1 effector cells, and are recognized as having a central role in the establishment of T-cell memory and peripheral immune tolerance. DC could be exploited as targets for therapy in asthma and allergic rhinitis.
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