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[Study on extracting oil of radix Angelica sinensis with supercritical CO2]
Shiming Nie1, Guizhi Zhang, Pengtao Zhang
1Pharmaceutical Aademy, Hubei College of TCM, Wuhan.
Objective:
To study the extraction of angelica oil by SFE-CO2 (CO2 Supercritical Fluid Extraction).
Methods:
Investigating the influence of the granule size of medical material, extraction temperature, extraction pressure, extraction time, releasing and separating condition on the extraction of angelica oil by the orthogonal design and other methods.
Results:
The optimum extraction is as follows: the granule size of medical material, 40 mu; extraction temperature, 40 degrees C; extraction pressure, 25Mpa; extraction time, 2 hours; flow of CO2, 20 L/h; pressure of separation pot I, 8Mpa; temperature of separation pot I, 50 degrees C; pressure of separation pot II, 6Mpa; temperature of separation pot II, 50 degrees C.
Conclusion:
The optimum extraction has high extraction ratio of angelica oil. The optimum extraction is reasonable and practicable.
