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Optimizing resynchronization therapy: can we increase the number of true responders?
1Sunrise Hospital and Medical Center and Cardiovascular Consultants of Nevada, Las Vegas, Nevada 89109, USA. rdoshi@earthlink.net
Journal of Cardiovascular Electrophysiology
|September 6, 2005
Summary
Cardiac resynchronization therapy (CRT) improves heart function but some patients do not respond. This review explores maximizing CRT benefits and if device programming advances can increase patient response rates.
Area of Science:
- Cardiology
- Biomedical Engineering
Background:
- Cardiac resynchronization therapy (CRT) is a standard treatment for heart failure with interventricular conduction delay.
- Despite proven efficacy, a significant nonresponder rate exists for CRT.
Purpose of the Study:
- To review challenges in maximizing biventricular pacing benefits.
- To investigate if advanced device programming can improve CRT response rates.
Main Methods:
- Literature review of studies on CRT programming and patient response.
- Analysis of factors influencing CRT efficacy.
Main Results:
- Nonresponse to CRT remains a clinical challenge.
- Potential for programming advancements to enhance patient outcomes.
Conclusions:
- Optimizing CRT programming is crucial for improving patient response.
- Further research into advanced device algorithms may increase the number of CRT responders.