Related Experiment Video
Updated: Aug 16, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
[Anaphylaxis: initial management]
V Morel1, F P Sarasin, C Hauser
1Service d'immuno-allergologie, Département de médecine interne, HUG, 1211 Genève 14. Vincent.Morel@hcuge.ch
Abstract:
Anaphylaxis is an immediate systemic reaction caused by an external agent. Its initial management depends on the severity of the reaction. In case of benign to moderate reaction, anti-histamine and steroid treatment are sufficient to control the process, and management is ambulatory. A severe reaction (hypotension, dyspnea) can be life threatening and adrenalin administration by the intramuscular route is indicated. In this case, it is advocated to observe the evolution for 24 hours in the hospital and the patient should be prescribed adrenaline auto-injectors. It is recommended that individuals who have experienced anaphylaxis should receive consultation from an allergist regarding diagnosis, prevention and treatment.
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