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[Endocarditis due to Pasteurella sp. Two cases].

F Camou1, O Guisset, S Pereyre

  • 1Service de médecine interne et maladies infectieuses, CHU Haut-Lévêque, avenue Magellan, 33604 Pessac cedex, France. fabrice.camou@chu-bordeaux.fr

Medecine Et Maladies Infectieuses
|October 29, 2005
PubMed
Summary
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Human pasteurellosis, a rare systemic infection, can cause endocarditis following animal contact. This infection has a high mortality rate, especially in immunocompromised individuals, necessitating prompt diagnosis and treatment.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Human pasteurellosis is typically a localized infection resulting from animal contact.
  • Systemic Pasteurella spp. infections are uncommon, with endocarditis being exceptionally rare.

Observation:

  • This study reviews 31 cases of Pasteurella spp. endocarditis, including two new cases.
  • The infection predominantly presents as an acute form (64% of cases).
  • Aortic and mitral valves are equally affected.

Findings:

  • Animal contact is a documented risk factor in 65% of cases.
  • Pasteurella multocida is the most frequently identified species.
  • The overall mortality rate is 40%, increasing to 57% in immunocompromised patients.

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Implications:

  • The severe prognosis underscores the need for early diagnosis of Pasteurella spp. endocarditis.
  • Effective and timely medicosurgical treatment is crucial but not yet standardized.
  • Understanding risk factors like animal contact is vital for prevention and management strategies.