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Cough and the common cold: ACCP evidence-based clinical practice guidelines
The common cold is the most frequent cause of acute cough, often due to upper airway irritation. Post-cold cough may stem from inflammation, potentially leading to a persistent upper airway cough syndrome.
Area of Science:
- Respiratory Medicine
- Infectious Diseases
- Clinical Research
Background:
- The common cold is a prevalent upper respiratory tract infection.
- Cough is a common symptom associated with the common cold.
Purpose of the Study:
- To conduct a literature review on the relationship between cough and the common cold.
- To elucidate the mechanisms and etiology of cough in the context of the common cold.
Main Methods:
- Literature search of MEDLINE database (1980-2004) using terms 'cough' and 'common cold'.
- Inclusion of case series and prospective descriptive clinical trials.
- Review of pertinent references from selected studies.
Main Results:
- The common cold is the most common cause of acute cough, likely due to upper airway irritation.
- Viral upper respiratory infections frequently cause rhinosinusitis, with imaging abnormalities often not indicative of bacterial infection.
- Abnormalities on sinus imaging during a cold are typically viral in origin.
Conclusions:
- Cough associated with the common cold is the leading cause of acute cough.
- Postinfectious cough can result from an inflammatory response to viral upper respiratory infections.
- Persistent cough may be classified as upper airway cough syndrome and may require intervention.
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