Related Experiment Video
Updated: Aug 9, 2026
09:48
An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
Ovarian primary primitive neurectodermal tumor coexisting with endometrioid adenocarcinoma: a case report
Gabor Fischer1, Kunle Odunsi, Shashi Lele
1Department of Pathology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
Summary
This case study details a rare ovarian tumor combining primitive neurectodermal tumor and endometrioid adenocarcinoma. The patient responded well to surgery and chemotherapy, remaining asymptomatic six months post-treatment.
Area of Science:
- Gynecologic Oncology
- Pathology
- Surgical Oncology
Background:
- Primary ovarian tumors are common, but mixed histology is rare.
- Primitive neurectodermal tumors (PNETs) are aggressive malignancies typically found in the central nervous system.
- Endometrioid adenocarcinoma is a common type of ovarian cancer.
Observation:
- A 78-year-old woman presented with abdominal pain and weight loss.
- Initial staging revealed disseminated disease.
- Histopathological examination confirmed a mixed ovarian tumor: PNET and endometrioid adenocarcinoma.
Findings:
- The patient underwent debulking surgery followed by chemotherapy.
- Post-treatment, the patient remained asymptomatic at the 6-month follow-up.
- This suggests a potential treatment efficacy for this rare mixed ovarian tumor.
Implications:
- This case highlights the importance of considering rare tumor types in gynecologic oncology.
- Aggressive management including surgery and chemotherapy may be effective for mixed PNET and endometrioid adenocarcinoma of the ovary.
- Further research is warranted to understand the behavior and optimal treatment of such rare ovarian malignancies.
