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Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells
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Nitric oxide activates TRP channels by cysteine S-nitrosylation

Takashi Yoshida1, Ryuji Inoue, Takashi Morii

  • 1Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.

Nature Chemical Biology
|September 26, 2006
PubMed
Summary

Nitric oxide (NO) activates TRP channels, a novel mechanism involving cysteine S-nitrosylation. This discovery identifies a new functional category of cellular receptors, expanding our understanding of NO signaling pathways.

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