Interleukin-2 concentration in hypothalamic structures of rats receiving peptides during mild stress
S V Barabanova1, Z E Artyukhina, T B Kazakova
1Department of General Pathology and Pathophysiology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg.
Bulletin of Experimental Biology and Medicine
|December 13, 2006
Abstract:
The number of hypothalamic IL-2-containing cells changed in rats receiving Vilon and Epithalon during mild stress (handling). The number of IL-2-positive cells in hypothalamic structures decreased 24 h after intramuscular injection of Epithalon and 2 h after intranasal administration of the test peptides. Adaptation of animals to experimental conditions prevented the decrease in the number of IL-2-positive cells in the supraoptic nucleus after intranasal administration of Epithalon.


