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Updated: Jul 16, 2026

A Unified Methodological Framework for Vestibular Schwannoma Research
Published on: June 20, 2017
Modern management of vestibular schwannomas
Jean Régis1, Pierre Hughes Roche, Christine Delsanti
1Departments of Functional Neurosurgery and ENT Surgery, Timone University Hospital, and Skull Base Neurosurgery Department, Sainte Marguerite, Marseille, France.
Abstract:
Within the last 3 decades, microsurgery and stereotactic radiosurgery (SRS) have become well-established management options for vestibular schwannomas (VSs). Advancement in the management of VSs can be separated into three periods: the microsurgical pioneer period, the demonstration of SRS as a first-line therapy for small and medium-sized VSs, and currently, a period of SRS maturity based on a large worldwide patient accrual. The Marseille SRS experience includes 1,500 patients, with 1,000 patients having follow-up longer than 3 years. A long-term tumor control rate of 97%, transient facial palsy lower than 1%, and a probability of functional hearing preservation between 50 and 95% was achieved in this large series of patients treated with state-of-the-art SRS.
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