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Updated: Jul 16, 2026
05:22
Ex vivo Culture of Human Placental Explants for the Study of Viral Transmission Across the Maternal-Fetal Interface
Published on: December 30, 2025
[Emerging viral infectious diseases and pregnancy]
P-F Ceccaldi1, P Longuet, L Mandelbrot
1Service de gynécologie-obstétrique, CHU Louis-Mourier, APHP, université Paris-VII, 178, rue des Renouillers, 92701 Colombes, France. secretariat.mandelbrot@lmr.aphp.fr
Gynecologie, Obstetrique & Fertilite
|March 21, 2007
Summary
Emerging infectious diseases pose risks to pregnant individuals and newborns. This review details the perinatal management strategies for H5N1, SARS Coronavirus, Chikungunya, and West Nile virus infections.
Area of Science:
- Virology
- Epidemiology
- Maternal-Fetal Medicine
Context:
- Improved epidemiologic monitoring has led to increased identification of emerging infectious diseases.
- These infections present significant risks to maternal health and fetal development.
- Understanding and managing these risks during pregnancy is crucial.
Purpose:
- To review the literature on frequently reported emergent viruses.
- To discuss the implications of these viral infections during pregnancy.
- To outline perinatal management strategies for affected pregnancies.
Summary:
- This literature review focuses on H5N1 influenza, SARS Coronavirus, Chikungunya, and West Nile virus.
- It examines the potential adverse maternal and fetal outcomes associated with these emergent viral infections.
- The review details current approaches to perinatal care for pregnant individuals diagnosed with these viruses.
Impact:
- Provides critical information for clinicians managing pregnancies complicated by emergent viral infections.
- Highlights the importance of vigilant surveillance and timely intervention.
- Contributes to improved understanding of viral transmission and its impact on pregnancy outcomes.
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