Related Experiment Video
Updated: May 1, 2026

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies
Published on: July 4, 2017
Other causes of pediatric deformity
Amer F Samdani1, Phillip B Storm
1Shriner's Hospital for Children, Philadelphia, PA 19027, USA. amersamdani@yahoo.com <amersamdani@yahoo.com>
Pediatric spine deformities encompass scoliosis and kyphosis from various causes. This review details congenital scoliosis classification, natural history, and management, alongside neuromuscular scoliosis etiologies.
Area of Science:
- Orthopedics
- Pediatric Spine Deformity
- Spinal Disorders
Background:
- Pediatric spine deformity presents diverse clinical manifestations including scoliosis, kyphosis, and lordosis.
- Etiologies range from idiopathic and congenital to neuromuscular, traumatic, iatrogenic, and radiation-induced causes.
Purpose of the Study:
- To provide a comprehensive overview of pediatric spine deformities.
- To discuss the classification, natural history, and management of congenital scoliosis.
- To explore the etiologies of neuromuscular scoliosis.
Main Methods:
- Literature review and synthesis of existing research on pediatric spine deformities.
- Detailed discussion of congenital scoliosis characteristics.
- Analysis of etiologies contributing to neuromuscular scoliosis.
Main Results:
- Congenital scoliosis classification and natural history are elucidated.
- Management strategies for congenital scoliosis are presented.
- Key etiologies for neuromuscular scoliosis are identified.
Conclusions:
- Understanding the diverse causes of pediatric spine deformity is crucial for effective management.
- Congenital and neuromuscular scoliosis represent significant subtypes requiring specific diagnostic and therapeutic approaches.
Related Concept Videos
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Teratogenicity
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Disorders of the Nervous Tissue
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...

