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Updated: Jul 13, 2026

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
Published on: February 23, 2020
Transcranial magnetic stimulation: a primer.
1Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA. hallettm@ninds.nih.gov
Transcranial magnetic stimulation (TMS) is a noninvasive brain stimulation technique. It uses magnetic fields to map brain function and is being developed for therapeutic uses.
Area of Science:
- Neuroscience
- Neuromodulation
- Brain Stimulation Techniques
Background:
- Transcranial magnetic stimulation (TMS) is a noninvasive method to stimulate the human brain.
- It involves generating a magnetic field via a coil to excite or inhibit targeted brain regions.
Purpose of the Study:
- To explore the capabilities of TMS in mapping brain function.
- To investigate the potential of TMS for therapeutic applications.
Main Methods:
- Generating brief, high-intensity magnetic fields using a magnetic coil.
- Applying magnetic stimulation to map sensory, motor, and cognitive functions.
- Utilizing repetitive TMS to influence brain function.
Main Results:
- TMS can influence brain areas beneath the coil, including the motor cortex.
- The technique successfully mapped various sensory, motor, and cognitive functions.
- TMS demonstrated clinical utility and potential for therapeutic development.
Conclusions:
- TMS is a versatile tool for noninvasive brain mapping and functional exploration.
- Repetitive TMS shows promise for developing new therapeutic interventions.
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