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Updated: Jul 8, 2026

Histological Quantification of Chronic Myocardial Infarct in Rats
Published on: December 11, 2016
Mid-ventricular hypertrophic obstructive cardiomyopathy presenting with acute myocardial infarction
Yuichi Sato1, Naoya Matsumoto, Shinro Matsuo
1Department of Cardiology, Nihon University School of Medicine, Tokyo, Japan. yuichis@med.nihon-u.ac.jp
Abstract:
Mid-ventricular hypertrophic obstructive cardiomyopathy is a rare type of cardiomyopathy that can be accompanied by apical aneurysm. We report the case of a patient who presented with ventricular fibrillation, ST-segment elevation on electrocardiography, and cardiac-enzyme elevation, in the presence of normal coronary arteries. Echocardiography and magnetic resonance imaging showed an hourglass appearance of the left ventricle with an aneurysm in the apex. Left-heart catheterization and continuous-wave Doppler echocardiography revealed a pressure gradient between the apical and basal chambers of the left ventricle. Impaired coronary artery circulation might play a role in the development of mid-ventricular obstruction in patients with mid-ventricular hypertrophic obstructive cardiomyopathy.
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