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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

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Group risks, risks to groups, and group engagement in genetics research.

Daniel M Hausman¹

¹University of Wisconsin-Madison, USA.

Kennedy Institute of Ethics Journal

|March 28, 2008

Summary

Genetic research poses risks of group harms. Engaging with affected groups can mitigate these harms, but different harms require distinct engagement strategies.

Area of Science:

Bioethics
Sociology of Science

Background:

Genetic research presents unique ethical challenges.
Understanding group harms is crucial for responsible scientific conduct.

Purpose of the Study:

To differentiate between individual and group-based harms arising from genetic research.
To explore how community engagement can mitigate identified risks.

Main Methods:

Conceptual analysis of group harm types.
Review of ethical considerations in genetic research.

Main Results:

Distinguishes harms to individuals due to group membership from harms to structured groups.
Identifies genetic research as a source of both harm types.
Proposes tailored engagement strategies for different group harms.

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Conclusions:

Genetic research necessitates a nuanced approach to mitigating group harms.
Effective risk mitigation requires distinct engagement strategies for distinct group harms.