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[Diagnosis, treatment and prevention of measles]
L Lacroix1, E Delaporte, C A Siegrist
1Hôpital des Enfant, HUG, 1211 Genève 14. laurence.lacroix@hcuge.ch
Abstract:
Measles is a highly contagious disease characterized by respiratory symptoms, rash and fever. Complications are common. Despite national recommendations concerning the need to vaccinate children with 2 doses of MMR vaccine (at age 12 months and between 15 and 24 months), epidemic outbursts still happen. The treatment of infected children is purely supportive, whereas susceptible household contacts may benefit from IVIG or catch up with vaccination depending on their age and the time spent since the contact. This paper defines a practical approach for measles infected cases and contact patients.
Insights
Measles outbreaks persist despite MMR vaccination recommendations. This paper outlines a practical management approach for infected children and their susceptible contacts, focusing on supportive care and post-exposure interventions.
Area of Science:
- Pediatrics
- Infectious Diseases
- Immunology
Context:
- Measles remains a significant public health concern, characterized by high contagiousness and potential complications.
- Despite established vaccination schedules, including two doses of the measles, mumps, and rubella (MMR) vaccine, epidemic outbreaks continue to occur.
- Current management for infected children is supportive, with interventions for contacts varying based on age and exposure time.
Purpose:
- To define a practical clinical approach for managing measles cases.
- To outline strategies for the management of susceptible household contacts of measles-infected individuals.
- To address the ongoing challenge of measles outbreaks despite vaccination efforts.
Summary:
- Measles presents with respiratory symptoms, rash, and fever, often leading to complications.
- Management of infected children is supportive.
- Susceptible contacts may receive intravenous immunoglobulin (IVIG) or timely catch-up vaccination.
Impact:
- Provides a clear management framework for healthcare providers dealing with measles.
- Aims to reduce the incidence and impact of measles outbreaks.
- Highlights the importance of timely post-exposure prophylaxis for measles prevention.
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