[The effect of UV-radiation on the metabolic activity of human blood granulocytes]

E V Men'shchikova, N K Zenkov, D I Azbel'

Voprosy Meditsinskoi Khimii

|January 1, 1991

Abstract:

Influence of UV irradiation (254 nm) on chemoluminescence of blood granulocytes was studied in patients with chronic unspecific lung impairments. Chemoluminescence of leukocytes was decreased after blood irradiation at the rate 10 J/ml as well as after the first course of the UV irradiated blood transfusion. At the same time, high dissimilarity of reactions to the irradiation was found in individual patients: in patients with low initial parameters of metabolism a stable decrease of chemoluminescence was observed to the 2nd, 3d and 4th courses of the irradiation, while in patients with high parameters--only to the 2nd course. This suggests that functional activity of phagocytes may be altered due to UV irradiation effects.

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Abstract:

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