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Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device
Published on: May 2, 2025
Brain tumours in children
G S Shah1, P Paudel, M Srivastav
1Deparment of Pediatrics, B. P. Koirala Institute of Health Sciences, Dharan, Nepal. gaurisshah@yahoo.com
Kathmandu University Medical Journal (KUMJ)
|September 5, 2008
Summary
This case report details a rare instance of brain stem gliomas in a pediatric patient. Clinical and imaging data confirmed the diagnosis, highlighting the importance of recognizing subtle neurological signs.
Area of Science:
- Neuro-oncology
- Pediatric Neurology
Background:
- Brain stem gliomas are rare central nervous system tumors, particularly in pediatric populations.
- Early diagnosis is crucial for effective management and improved patient outcomes.
Observation:
- A 10-year-old female presented with a 5-year history of abnormal movements.
- Recent onset of left-sided mouth deviation and difficulty walking were noted.
Findings:
- Clinical presentation and imaging studies were indicative of brain stem gliomas.
- The case underscores the diagnostic challenges associated with rare neurological conditions.
Implications:
- This case contributes to the limited literature on pediatric brain stem gliomas.
- Highlights the need for comprehensive diagnostic approaches in pediatric neurology.
