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Related Concept Videos

The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

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Related Experiment Video

Updated: Jul 2, 2026

Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device
07:44

Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device

Published on: May 2, 2025

Brain tumours in children.

G S Shah1, P Paudel, M Srivastav

  • 1Deparment of Pediatrics, B. P. Koirala Institute of Health Sciences, Dharan, Nepal. gaurisshah@yahoo.com

Kathmandu University Medical Journal (KUMJ)
|September 5, 2008
PubMed
Summary
This summary is machine-generated.

This case report details a rare instance of brain stem gliomas in a pediatric patient. Clinical and imaging data confirmed the diagnosis, highlighting the importance of recognizing subtle neurological signs.

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Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting
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Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting

Published on: September 25, 2012

Related Experiment Videos

Last Updated: Jul 2, 2026

Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device
07:44

Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device

Published on: May 2, 2025

Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting
08:14

Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting

Published on: September 25, 2012

Area of Science:

  • Neuro-oncology
  • Pediatric Neurology

Background:

  • Brain stem gliomas are rare central nervous system tumors, particularly in pediatric populations.
  • Early diagnosis is crucial for effective management and improved patient outcomes.

Observation:

  • A 10-year-old female presented with a 5-year history of abnormal movements.
  • Recent onset of left-sided mouth deviation and difficulty walking were noted.

Findings:

  • Clinical presentation and imaging studies were indicative of brain stem gliomas.
  • The case underscores the diagnostic challenges associated with rare neurological conditions.

Implications:

  • This case contributes to the limited literature on pediatric brain stem gliomas.
  • Highlights the need for comprehensive diagnostic approaches in pediatric neurology.