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Updated: Jun 29, 2026

Clinical Application of Phase Angle and BIVA Z-Score Analyses in Patients Admitted to an Emergency Department with Acute Heart Failure

Clinical Application of Phase Angle and BIVA Z-Score Analyses in Patients Admitted to an Emergency Department with Acute Heart Failure

Published on: June 30, 2023

[pH-impedancemetry: clinical implications].

David Bertolini¹, Sabine Roman, Jean-Marc Dumonceau

¹Division de gastroentérologie et d'hépatologie, HUG, 1211 Geneve 14. david.bertolini@hcuge.ch

Revue Medicale Suisse

|October 4, 2008

Summary

This summary is machine-generated.

pH-impedance monitoring offers a more comprehensive assessment of gastroesophageal reflux disease than traditional pH monitoring. This advanced technique detects all reflux types, improving diagnosis for patients with atypical symptoms or those unresponsive to treatment.

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Clinical Application of Phase Angle and BIVA Z-Score Analyses in Patients Admitted to an Emergency Department with Acute Heart Failure

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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

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Published on: June 10, 2025

Area of Science:

Gastroenterology
Digestive Health
Medical Diagnostics

Background:

Gastroesophageal reflux disease (GERD) is a prevalent condition often diagnosed clinically.
Traditional pH monitoring, a long-standing diagnostic tool, primarily measures esophageal acid exposure.
Limitations of pH monitoring include its inability to detect non-acidic reflux events.

Purpose of the Study:

To introduce and evaluate pH-impedance monitoring as an advanced diagnostic technique for GERD.
To compare the capabilities of pH-impedance monitoring with conventional pH monitoring.
To highlight the diagnostic utility of pH-impedance monitoring in complex GERD cases.

Main Methods:

Utilized pH-impedance monitoring, a novel technique for assessing esophageal intraluminal contents.
Analyzed the detection of all reflux types, including gas-liquid, acid, and weakly acidic reflux.
Correlated reflux events with patient symptoms to establish a relationship.

Main Results:

pH-impedance monitoring successfully identifies all types of reflux events (acidic, weakly acidic, and non-acidic).
This method establishes a direct relationship between reflux episodes and the occurrence of symptoms.
Weakly acid reflux, often missed by pH monitoring, is detectable with pH-impedance.

Conclusions:

pH-impedance monitoring provides a more comprehensive evaluation of GERD compared to traditional pH monitoring.
It is particularly valuable for diagnosing patients with atypical GERD symptoms or refractory symptoms.
This technique enhances the diagnostic accuracy for GERD by detecting all refluxogenic phenomena.