[Ceruloplasmin levels in patients with chronic obstructive bronchopneumopathy]

The seric levels of ceruloplasmin in a group of 20 patients suffering of chronic obstructive lung disease were studied. Levels in this group of patients (51.42 +/- 11.15 mg/dl) (p less than 0.005) were significantly higher than those of the control group (36.59 +/- 13.37 mg/dl). There was no correlation between ceruloplasmin levels and PaO2, PaCO2, SaO2, HCO3- measurements. Results show a possible oxidation reaction; owing to the fact that ceruloplasmin is a general oxidase which, combined with an antioxidant stimulus of patients with chronic respiratory insufficiency, can produce this reaction.