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Updated: Jun 24, 2026
Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
Published on: March 11, 2016
Fundus autofluorescence in cone dystrophy
Nan-Kai Wang1, Chai Lin Chou, Luiz H Lima
1Bernard and Shirlee Brown Glaucoma Laboratory, Edward S. Harkness Eye Institute, 160 Fort Washington Ave, Research Annex, New York, NY 10032, USA.
Purpose:
To describe fundus autofluorescence (FAF) finding in a case of cone dystrophy.
Methods:
Interventional case report.
Results:
A 23-year-old woman presented with increasing photophobia and decreasing vision in both eyes for 2 years. Fundus examination showed several drusen-like dots. FAF revealed hyper-autofluorescence in the foveola. Electroretinogram (ERG) demonstrated a pure "cone" dystrophy.
Conclusion:
Hyper-autofluorescence in the foveola is a non-specific manifestation of photoreceptor-retinal pigment epithelium dysfunction. ERG studies are essential for accurate diagnosis.
