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Myeloproliferative disorders and the hyperviscosity syndrome
Bruce D Adams1, Russell Baker, J Abraham Lopez
1Department of Clinical Investigation, William Beaumont Army Medical Center, El Paso, TX 79920-5001, USA. bruce.adams@amedd.army.mil
Emergency Medicine Clinics of North America
|August 4, 2009
Summary
Myeloproliferative disorders can cause serum hyperviscosity syndrome, leading to emergent symptoms. Prompt recognition and management, including plasma exchange, are crucial for these complex hematologic conditions.
Area of Science:
- Hematology
- Emergency Medicine
Background:
- Myeloproliferative disorders and serum hyperviscosity syndrome present with emergent symptoms.
- Hyperviscosity results from abnormal elevations in blood's cellular or protein components.
Purpose of the Study:
- To highlight the emergent nature of myeloproliferative disorders and serum hyperviscosity syndrome.
- To inform emergency medicine providers about recognizing and managing these conditions.
Main Methods:
- Review of clinical presentations and management strategies for hyperviscosity syndrome.
- Emphasis on supportive care and early definitive treatments like apheresis.
Main Results:
- Classic hyperviscosity syndrome involves bleeding, visual disturbances, and neurologic signs.
- Rapid intervention is necessary for patients with these emergent presentations.
Conclusions:
- Emergency medicine providers must be prepared for rapid management of hyperviscosity syndrome.
- Early hematology consultation is essential for optimal patient outcomes.
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