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Updated: Jun 19, 2026

Transillumination-Assisted Dissection of Specific Stages of the Mouse Seminiferous Epithelial Cycle for Downstream Immunostaining Analyses
Published on: October 7, 2020
Spermatogenesis and cycle of the seminiferous epithelium
Rex A Hess1, Luiz Renato de Franca
1Department of Veterinary Biosciences, University of Illinois, Urbana, IL 61802-6199, USA. rexhess@uiuc.edu
Abstract:
Spermatogenesis is a complex biological process of cellular transformation that produces male haploid germ cells from diploid spermatogonial stem cells. This process has been simplified morphologically by recognizing cellular associations or 'stages' and 'phases' of spermatogenesis, which progress through precisely timed and highly organized cycles. These cycles of spermatogenesis are essential for continuous sperm production, which is dependent upon numerous factors, both intrinsic (Sertoli and germ cells) and extrinsic (androgens, retinoic acids), as well as being species-specific.
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