Related Experiment Video
Updated: Jun 18, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
[Stroke-psychosis. Description of two cases]
S Santos1, O Alberti, T Corbalán
1Servicio de Neurología, Hospital Clínico Universitario Lozano Blesa, San Juan Bosco, 15, 50009 Zaragoza, Spain. ssantosl@yahoo.com
Acute psychosis following stroke is rare but linked to strategic infarcts. This study highlights two cases of stroke-induced psychosis, emphasizing the vascular origin and potential dysfunction in brain circuits.
Area of Science:
- Neuroscience
- Neurology
- Psychiatry
Background:
- Neuropsychiatric symptoms like hallucinations and delusions are uncommon stroke-related complications.
- These symptoms can manifest as acute psychosis of organic origin.
- Such cases often correlate with strategic infarcts in specific brain regions (caudate nucleus, striatum, thalamus).
Observation:
- Two cases of stroke-induced psychosis are presented.
- Case 1: A 67-year-old male experienced sudden delusions of persecution, with recovery in three months. MRI showed infarcts in the caudate nucleus.
- Case 2: A 49-year-old male presented with sudden delusions and gustative hallucinations, resolving in three months. MRI revealed a thalamic infarct.
Findings:
- Both cases suggest a vascular origin for psychosis, evidenced by sudden onset and recovery.
- Acute ischemic lesions were identified in strategic brain territories.
- The findings support the link between specific stroke locations and psychosis development.
Implications:
- The study discusses the potential vascular etiology of psychosis.
- It explores the underlying psychopathogenic mechanism involving prefrontal cortico-subcortical circuit dysfunction.
- Understanding these mechanisms can aid in diagnosing and managing stroke-related neuropsychiatric conditions.
Related Concept Videos
Psychosis and Antipsychotic Drugs: Overview
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Psychosis: Goals of Pharmacotherapy
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...
Schizophrenia
Personality Disorders: Schizotypal and Histrionic
Schizotypal Personality Disorder: Eccentric Behavior and Social Withdrawal
Schizotypal personality disorder is marked by odd or eccentric...