[Immunereactivity of hypothalamic orexin-containing neurons after restraint and cold stress in rats]

Studying of immunereactivity of orexin-containing neurons after restraint and cold stress has allowed to reveal a selective change of a degree ofimmunereactivity ofhypothalamic orexin-containing neurons. Orexin-containing neurons are located in structures 28, 29, 31 levels of brain slices and have the different degree of immunereactivity that indicates functional heterogeneity of a population of hypothalamic orexin-containing neurons. Structures and zones of hypothalamus involved in development of complex brain responses to restraint or cold stress applications were identified. Changes of immunereactivity of orexin-containing neurons located in the areas involved in system of regulation ofthermogenesis (DMH, PH and some zones LHA) suggest a possibility of orexin-containing neurons participation in thermoregulation.