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Updated: Jun 15, 2026

Genetic Manipulation of the Mouse Developing Hypothalamus through In utero Electroporation
Published on: July 24, 2013
Ontogeny of Cl- homeostasis in mouse hypoglossal nucleus
Akihito Okabe1, Akiko Arata, Yoshitaka Oku
1Division of Physiome, Department of Physiology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan. okabe@hyo-med.ac.jp
Abstract:
We tested the immunoreactivity of KCC2 using KCC2 antibody in the developmental mouse medulla. Age-dependent changes in immunoreactivity were remarkable in the hypoglossal nucleus, and interestingly, the immunoreactivity in the hypoglossal nucleus relative to the dorsal vagal nucleus at P0 appeared to be higher than that of P7. Thus Cl(-) homeostasis in the hypoglossal nucleus might be differentially regulated in the developmental stage.
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