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Updated: Jun 12, 2026

Laser Capture Microdissection of Neurons from Differentiated Human Neuroprogenitor Cells in Culture
Published on: September 16, 2013
[Clinical application of the Colorado-microdissection needle in neurosurgery]
Shiro Baba1, Takayuki Matsuo, Ryujiro Ushijima
1Department of Neurosurgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Abstract:
The steel scalpel and scalp clips have been commonly used for scalp incision in many neurosurgical procedures. Electrocautery is used mainly for subcutaneous and deep-layer dissection. The use of electrocautery on scalp incision has been avoided because of possible adverse events such as wound dehiscence and infection. We report our experience in Colorado-microdissection needle electrocautery for scalp incisions performed in our institution between November, 2006 and March, 2009. The rate of wound infection was compared in patients using the microdissection needle (100 procedures, n=93) and those using the steel scalpel/clips (n=261) during the same period. In patients using the microdissection needle, wound healing delay was not observed. Wound infection developed in only one procedure (1.0%) with the microdissection needle, and it developed in 6 procedures (2.2%) with the steel scalpel/clips, although this did not reach statistical significance (p=0.34). The use of electrocautery tended to cause little tissue distortion during fine dissection and it reduced blood loss. In conclusion, Colorado-microdissection needle electrocautery for scalp incisions could be safe and quite useful in neurosurgical procedures.

