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Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation
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Mesp-family genes are required for segmental patterning and segmental border formation

Yumiko Saga1, Yu Takahashi

  • 1Division of Mammalian Development, National Institute of Genetics, Yata 1111, Mishima 411-8540, Japan. ysaga@lab.nig.ac.jp

Advances in Experimental Medicine and Biology
|November 3, 2010
PubMed
Summary

Somite patterning relies on precise gene regulation in the presomitic mesoderm (PSM). Hes7 in the posterior PSM and Mesp2 in the anterior PSM, interacting with Notch signaling, orchestrate somitogenesis.

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