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Updated: Jun 5, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Obstructive sleep apnea patients voice analysis
A T Cernomaz1, Daniela Boişteanu, Raluca Vasiluţă
1Disciplina de Pneumologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa laşi.
Obstructive sleep apnea (OSA) may cause larynx abnormalities. This study analyzes voice acoustics in OSA patients to explore a potential non-invasive screening test for these changes.
Area of Science:
- Laryngology
- Acoustic analysis
- Sleep medicine
Background:
- Obstructive sleep apnea (OSA) is often associated with laryngeal abnormalities, affecting vocal tract structure and function.
- Non-invasive methods for exploring these changes are needed.
Purpose of the Study:
- To evaluate acoustic voice features in patients with OSA compared to controls.
- To assess the potential of voice analysis as a screening tool for OSA-related laryngeal changes.
Main Methods:
- Sustained vowel phonations ('a', 'i') were recorded from OSA patients and matched controls.
- Acoustic parameters, including fundamental frequency and amplitude variation, were analyzed.
Main Results:
- Preliminary analysis focused on specific acoustic parameters.
- Further development of parameters is ongoing to identify significant differences between groups.
Conclusions:
- Voice acoustic analysis shows promise for detecting laryngeal changes related to OSA.
- This approach could lead to a novel, non-invasive screening method for obstructive sleep apnea.
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