Related Experiment Video
Updated: Jun 5, 2026

09:59
An “All-laser” Endothelial Transplant
Published on: July 6, 2015
Laser-assisted subepithelial keratectomy retreatment surgery.
Colm McAlinden1, Jonathan Moore
1School of Biomedical Sciences, University of Ulster, Coleraine, United Kingdom. colm.mcalinden@gmail.com
Journal of Cataract and Refractive Surgery
|January 19, 2011
Summary
Laser-assisted subepithelial keratectomy (LASEK) retreatment is safe and effective for correcting residual refractive errors after initial LASEK. This study shows good visual outcomes and stability without using Mitomycin-C (MMC).
Area of Science:
- Ophthalmology
- Refractive Surgery
- Corneal Surgery
Background:
- Laser-assisted subepithelial keratectomy (LASEK) is a refractive surgical procedure.
- Residual refractive errors may necessitate retreatment after initial LASEK surgery.
- The use of Mitomycin-C (MMC) in LASEK procedures is a consideration for outcomes.
Purpose of the Study:
- To evaluate the outcomes of laser-assisted subepithelial keratectomy (LASEK) retreatment.
- To assess predictability, safety, efficacy, and stability of LASEK retreatment following prior LASEK.
- To determine outcomes without the use of Mitomycin-C (MMC) in retreatment.
Main Methods:
- Retrospective case series of 16 patients (23 eyes) undergoing LASEK retreatment.
- Wavefront-guided treatments performed using the Visx S4 Star excimer laser.
- Mitomycin-C (MMC) was not utilized in primary or retreatment procedures.
Main Results:
- Mean preoperative spherical equivalent (SE) of -3.61 D improved to +0.02 D six months post-retreatment.
- All eyes achieved uncorrected distance visual acuity (UDVA) of 6/6 or better.
- No eyes lost lines of corrected distance visual acuity (CDVA) or developed significant corneal haze.
Conclusions:
- LASEK retreatment following prior LASEK, without MMC, yields favorable predictability, safety, efficacy, and stability.
- The procedure effectively corrects residual refractive errors with good visual outcomes.
- This approach offers a viable option for patients needing repeat LASEK surgery.
