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Updated: Jun 5, 2026

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Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics
Published on: July 16, 2018
Ultrasensitive scanometric strategy for detection of matrix metalloproteinases using a histidine tagged peptide-Au
Wei Cheng1, Yunlong Chen, Feng Yan
1Key Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, P.R. China.
Abstract:
A simple scanometric strategy was developed for ultrasensitive assay of matrix metalloproteinases based on their discriminatory and proteolytic activity by integrating a newly designed peptide-gold nanoparticle probe, a nitrilotriacetic acid modified chip and silver signal amplification.

