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Updated: Jun 3, 2026

Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
Published on: April 27, 2014
Transcranial brain stimulation: clinical applications and future directions
Umer Najib1, Shahid Bashir, Dylan Edwards
1Department of Neurology, Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.
Noninvasive brain stimulation, specifically Transcranial Magnetic Stimulation (TMS), offers valuable insights into brain function and has therapeutic potential. Neuronavigated TMS precisely maps brain areas, aiding surgical planning and reducing invasive procedures.
Area of Science:
- Neuroscience
- Neurology
- Psychiatry
Background:
- Noninvasive brain stimulation is a key tool in cognitive neuroscience and neurophysiology.
- Transcranial Magnetic Stimulation (TMS) is effective for mapping causal brain-behavior relationships.
- Neuronavigated TMS offers precise functional anatomical information.
Purpose of the Study:
- To review the methodological aspects of TMS-based mapping.
- To discuss the clinical applications of TMS-based mapping.
- To explore future directions in TMS-based mapping.
Main Methods:
- Utilizing neuronavigated Transcranial Magnetic Stimulation (TMS).
- Mapping motor and nonmotor cortical areas.
- Visualizing individual functional anatomy for surgical planning.
Main Results:
- TMS establishes causal brain-behavior relations.
- Neuronavigated TMS aids presurgical planning effectively.
- Reduces the need for invasive mapping procedures.
Conclusions:
- TMS is a valuable investigative and therapeutic tool.
- Neuronavigated TMS enhances surgical interventions.
- TMS-based mapping has significant potential in clinical neurology and psychiatry.
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