Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Low-Dose Buprenorphine Initiations During Opioid and Sedative Weaning in Mechanically Ventilated Neurocritical Care Patients: A Retrospective Pilot Cohort Study.

Neurocritical care·2026
Same author

A vendor-neutral functional MRI acquisition protocol for multi-site studies.

Aperture neuro·2026
Same author

Buprenorphine Initiation During Extracorporeal Membrane Oxygenation Decreases Sedative and Opioid Exposure: A Retrospective Matched Case-Control Study.

Pharmacotherapy·2026
Same author

Pilot testing a multi-level stigma intervention to improve substance use care with providers in mental health settings: A cluster-randomized trial.

Journal of substance use and addiction treatment·2026
Same author

Longitudinal analysis of symptoms and healthcare utilization among daily cannabis-using persons living with HIV: impact of co-occurring cocaine use.

Journal of cannabis research·2026
Same author

Plasma neurofilament light is associated with hippocampal volume and memory performance but not functional connectivity in older adults with and without mild cognitive decline.

Aging brain·2026
Same journal

Multi-Contrast Human Brain CEST MRI at 11.7 T: First In Vivo Demonstration.

Magnetic resonance in medicine·2026
Same journal

Suppression of Oscillation and Ghosting in RF-Spoiled Gradient-Echo-Based Dynamic Imaging.

Magnetic resonance in medicine·2026
Same journal

A Simple, Dynamic Geometric Phantom for MRI and CT Reconstruction Pipelines: Beyond Shepp-Logan.

Magnetic resonance in medicine·2026
Same journal

7T 3D-EPI PCASL With High SNR Efficiency and Robustness to Through-Plane B<sub>0</sub> Field Gradients.

Magnetic resonance in medicine·2026
Same journal

A Comparison of Tissue Property Values Estimated Using Conventional Cardiac MRF and MT-Cardiac MRF.

Magnetic resonance in medicine·2026
Same journal

Dependence of the Extra-Cellular Diffusion Coefficient on the Fractions of Neurites and Cell Bodies in Gray Matter.

Magnetic resonance in medicine·2026
See all related articles

Related Experiment Video

Updated: Jun 3, 2026

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling
05:23

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

Published on: May 31, 2024

Real-time functional MRI using pseudo-continuous arterial spin labeling.

Luis Hernandez-Garcia1, Hesamoddin Jahanian, Mark K Greenwald

  • 1Functional MRI Laboratory, Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48105, USA. hernan@umich.edu

Magnetic Resonance in Medicine
|March 30, 2011
PubMed
Summary
This summary is machine-generated.

This study presents the first real-time system for arterial spin labeling functional MRI, enabling immediate analysis and visualization of brain activity during experiments. The method allows interactive adjustments and region selection for improved functional MRI data acquisition and analysis.

More Related Videos

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
12:29

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

Published on: May 30, 2011

Real-Time fMRI Brain Mapping in Animals
04:05

Real-Time fMRI Brain Mapping in Animals

Published on: September 24, 2020

Related Experiment Videos

Last Updated: Jun 3, 2026

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling
05:23

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

Published on: May 31, 2024

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
12:29

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

Published on: May 30, 2011

Real-Time fMRI Brain Mapping in Animals
04:05

Real-Time fMRI Brain Mapping in Animals

Published on: September 24, 2020

Area of Science:

  • Neuroimaging
  • Biophysics
  • Medical Physics

Background:

  • Arterial spin labeling (ASL) is a non-invasive MRI technique for measuring cerebral blood flow.
  • Functional MRI (fMRI) detects brain activity by changes in blood flow.
  • Real-time analysis of fMRI data can enhance experimental efficiency and data quality.

Purpose of the Study:

  • To implement and validate a real-time acquisition and analysis system for ASL-based fMRI.
  • To enable immediate feedback and interactive control during fMRI experiments.
  • To demonstrate the system's utility in dynamic functional brain imaging.

Main Methods:

  • Utilized a pseudo-continuous labeling scheme and spiral k-space acquisition trajectory.
  • Developed real-time image reconstruction, preprocessing, and regression analysis on a laptop.
  • Integrated interactive tools for data visualization and region-of-interest selection.

Main Results:

  • Successfully demonstrated real-time tracking of raw data, subtraction images, and t-statistic maps.
  • Enabled interactive adjustment of acquisition and labeling parameters with immediate visual feedback.
  • Validated the system through functional imaging experiments involving motor and visual tasks.

Conclusions:

  • The developed system provides the first real-time capability for ASL-based fMRI acquisition and analysis.
  • This real-time approach enhances user interaction and control over fMRI experiments.
  • The method shows promise for improving the efficiency and effectiveness of functional neuroimaging studies.