Related Experiment Video
Updated: Aug 17, 2026

07:15
Invasion of Human Cells by a Bacterial Pathogen
Published on: March 21, 2011
[Effect of small doses of diphtheria exotoxin on cell cultures]
Abstract:
High diphtheria exotoxin concentrations induced irreversible injuries to all the cultures under study (L, HeLa, spcv pzM). However, its final titres in the mentioned cells differed. HeLa and pzM cells, being highly sensitive, can be recommended for titration of dipheria exotoxin, instead of the expensive guinea pig tests. Low (subtoxic) doses produced cytoproliferative action and caused changes of the cell properties.

