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Updated: May 1, 2026

Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging
Published on: February 10, 2012
[Post-mortem angio-CT: a new diagnostic approach]
S Grabherr1, A Dominguez, P Mangin
1Centre universitaire romand de médecine légale, CHUV, Lausanne. silke.grabherr@chuv.ch
Abstract:
Post-mortem CT-angiography is a minimally invasive exam that allows the investigation of the vascular system in a very detailed way, impossible to realize during conventional autopsy. The research group for post-mortem angio-CT in Lausanne has developed a standardized protocol fora technique called "multi-phase post-mortem CT-angiography" that leads to an easy applicable performance of the exam and an increased diagnostic value. Additionally, new equipment including a perfusion device with single use sets as well as a special contrast agent for post-mortem investigations has been created. Using this technique, angio-CT permits to detect of the source of haemorrhages, vascular malformations, arteriosclerotic lesions as well as vascular occlusions and to visualize the vascular anatomy exactly.
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