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Updated: May 28, 2026
07:35
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
[Colorectal cancer--clinical course, epidemiologic and pathologic aspects]
1Universităţii de Medicină şi Farmacie "Gr. T. Popa Iaşi".
Summary
Colorectal cancer is a leading cause of death, particularly affecting males over 60. This study analyzed patient data to understand its incidence, manifestations, and location within the colon.
Area of Science:
- Oncology
- Gastroenterology
- Public Health
Background:
- Colorectal cancer (CRC) is a significant cause of mortality, surpassing gastric cancer in recent years.
- Understanding CRC's epidemiology and clinical presentation is crucial for public health strategies.
Purpose of the Study:
- To analyze the incidence, demographics, clinical manifestations, and tumor location of colorectal cancer.
- To provide insights into CRC patient characteristics for improved diagnosis and treatment.
Main Methods:
- Retrospective analysis of 644 patients diagnosed with colorectal cancer via colonoscopy (2000-2007).
- Inclusion of 279 surgically treated patients (2008-2010).
- Data collected from Iasi Gastroenterology and Hepatology Institute and "Sf. Spiridon" Hospital.
Main Results:
- CRC incidence is highest in males over 60 years old (male/female ratio 1.3).
- Common symptoms include intestinal transit disorder (97%), left-sided abdominal pain (82.82%), and constipation (67.89%).
- Tumors are predominantly located in the distal colon (75.9%) and frequently present as vegetative forms (89.91%).
Conclusions:
- Colorectal cancer disproportionately affects older males and presents with specific gastrointestinal symptoms.
- Distal colon tumors are more common, emphasizing the need for targeted screening and diagnostic efforts.
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