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Updated: May 26, 2026
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Sample Preparation and Transfer Protocol for In-Vacuum Long-Wavelength Crystallography on Beamline I23 at Diamond Light Source
Published on: April 23, 2021
Circular dichroism beamline B23 at the Diamond Light Source.
Rohanah Hussain1, Tamás Jávorfi, Giuliano Siligardi
1Diamond Light Source, Chilton, Didcot, Oxfordshire, UK. rohanah.hussain@diamond.ac.uk
Journal of Synchrotron Radiation
|December 22, 2011
Summary
The new B23 beamline at Diamond Light Source offers synchrotron radiation circular dichroism (SRCD) for structural biology. This advanced facility provides enhanced capabilities for researchers studying biological molecules.
Area of Science:
- Structural Biology
- Biophysical Chemistry
- Synchrotron Radiation Science
Background:
- Synchrotron radiation circular dichroism (SRCD) is a crucial technique for determining the secondary and tertiary structures of biological macromolecules.
- Advancements in synchrotron technology have enabled the development of dedicated SRCD beamlines with enhanced performance.
Purpose of the Study:
- To introduce the newly operational B23 SRCD beamline at Diamond Light Source, a UK-based third-generation synchrotron facility.
- To detail the characteristics, available ancillary facilities, and recent achievements of the B23 beamline for the scientific community.
Main Methods:
- Characterization of the B23 beamline's performance and capabilities for SRCD spectroscopy.
- Description of user-accessible ancillary equipment and support services.
Main Results:
- The B23 beamline is now operational and available to users, offering advanced SRCD capabilities.
- Summary of key technical specifications and initial scientific outcomes demonstrating the beamline's utility.
Conclusions:
- The B23 SRCD beamline represents a significant new resource for structural biology research in the UK and internationally.
- The facility is expected to facilitate novel investigations into the structure and function of biological molecules.
