Related Experiment Video
Updated: May 26, 2026

Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
Published on: February 21, 2011
[Effects of rush mat dust exposure and smoking on workers' FEV1.0]
Jin-Lei Chen1, Guo-Bing Xiao, Wen-Ming Kong
1Institute of Preventive Medicine Research, Medical School of Ningbo University, Zhejiang 315211, China.
Objective:
To study the effect of smoking and rush-mat dust exposure on pulmonary function.
Method:
122 rush-mat dust exposed workers and 118 controls without dust exposure were selected. Questionnaire and FEVY1.0 measurement were performed on them.
Results:
For dust exposure, FEV1.0% of cases (81.8% +/- 13.9%) was statistically lower than controls (95.9% +/- 15.3%) (t = -7.49, P < 0.01), the abnormal rate of FEV1.0% was 46.7% (57/122) for cases, statistically higher than controls (8.5%, 10/118), chi2 = 43.6, P < 0.01. For smoking, FEV1.0% of cases (82.02% +/- 12.9%) was statistically lower than controls (93.33% +/- 12.4%), t = -5.18, P < 0.05, the abnormal rate of FEV1.0% is 55.9% for cases, statistically higher than controls (16.7%), chi2 = 22.2, P < 0.05. The exposing ages of workers has negative correlation with FEV1.0% (R(S1) = -0.299, P = 0.0008). Exposure and smoking could affect FEV1.0% (Fe = 259.06, P < 0.01, F(s) = 42.42, P < 0.01), and their interactive effect on FEV1.0% was greater than single ones (F = 34.70, P < 0.01).
Conclusion:
Rush-mat dust exposure, smoking and their interaction have influence on FEV1.0%.
Related Concept Videos
Chronic Obstructive Pulmonary Disease-I: Introduction
Chronic Obstructive Pulmonary Disease I: Introduction
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Chronic Obstructive Pulmonary Disease II: Emphysema
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

