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Updated: May 25, 2026

Production and Testing of Antimicrobial Peptides and Their Mimics
Published on: April 10, 2026
[Research progress in fusion expression of antimicrobial peptides]
Qingshan Ma1, Zhanqiao Yu, Bing Han
1Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, China.
Abstract:
Antimicrobial peptides (AMPs) are of great significance in the field of food, feed and medicine due to their wide spectrum of antimicrobial activity and new mechanism of action different from conventional antibiotics. AMPs production from natural sources is usually limited, and chemical synthesis is not economically practical, especially for the production of long peptides. Therefore, heterologous expression of AMPs has been widely studied as an alternative, and fusion expression plays an important role in increasing production. The present review mainly focuses on the types and bioactivities of AMPs. In addition, the recent strategies to the most commonly used carrier proteins for fusion expression of AMPs and prospects for future research were also discussed.
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