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Updated: May 24, 2026

The Use of Thermal Infra-Red Imaging to Detect Delayed Onset Muscle Soreness
Published on: January 22, 2012
Muscle soreness and delayed-onset muscle soreness
Paul B Lewis1, Deana Ruby, Charles A Bush-Joseph
1Department of Diagnostic Radiology & Nuclear Medicine, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA. paul_lewis@rsh.net
Muscle soreness, including delayed-onset muscle soreness (DOMS), arises from microtrauma and inflammation. NSAIDs and continued exercise are recommended for managing symptoms and functional deficits.
Area of Science:
- Sports Medicine
- Exercise Physiology
- Muscle Physiology
Background:
- Muscle soreness presents in immediate and delayed-onset forms, sharing pain qualities and functional deficits.
- Delayed-onset muscle soreness (DOMS) involves muscle microtrauma, inflammation, fluid shifts, and potential spasms.
- Multiple mechanisms contribute to muscle soreness, not a single cause.
Purpose of the Study:
- To review the mechanisms and management of immediate and delayed-onset muscle soreness.
- To explore various treatment modalities for muscle soreness symptoms.
- To highlight reliable management strategies for muscle soreness.
Main Methods:
- Literature review of studies on muscle soreness mechanisms and treatments.
- Analysis of the pathways leading to muscle microtrauma and inflammation.
- Evaluation of diverse therapeutic modalities for symptom relief.
Main Results:
- Muscle soreness results from a complex interplay of six distinct mechanisms.
- DOMS progression involves microtrauma, inflammation, fluid/electrolyte shifts, and muscle spasms.
- Non-steroidal anti-inflammatory drugs (NSAIDs) and continued exercise are identified as reliable management methods.
Conclusions:
- Effective management of muscle soreness requires understanding its multifactorial nature.
- NSAIDs and continued exercise offer reliable relief for muscle soreness symptoms.
- Clinicians must carefully assess and manage muscle soreness and associated deficits.
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