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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
Carbonyl derivatives of boradiazaindacene via catalytic CO insertion
Gilles Ulrich1, Alexandre Haefele, Pascal Retailleau
1Laboratoire de Chimie Organique et Spectroscopies Avancées (LCOSA), UMR 7515 au CNRS, Université de Strasbourg, Ecole de Chimie, Polymères, Matériaux de Strasbourg (ECPM), 25 rue Becquerel, 67087 Strasbourg Cedex 02, France. gulrich@unistra.fr
Abstract:
A methodological study is presented dealing with carbopalladation reactions on BODIPY dyes bearing aryl-halogen functions. Using this technique, several ester and amide groups were efficiently introduced on the dyes. These changes do not affect the optical properties of the dyes and thus allow the construction of new BODIPY-based functional dyes with carboxylic anchoring groups or peptide links.
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