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Related Concept Videos

Social Anxiety Disorder01:28

Social Anxiety Disorder

Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
Anxiety: Overview01:18

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
Horney's Sociocultural Approach01:27

Horney's Sociocultural Approach

Karen Horney's psychoanalytic theories emphasize the potential for self-realization and the importance of addressing social and cultural, rather than biological, factors in personality development. She challenged traditional Freudian views, particularly Freud's concept of "penis envy," which she argued stemmed from cultural influences rather than inherent biological differences. Horney believed that any sense of inferiority in women was a result of societal conditioning, such as dependence on...
Panic Disorder01:27

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
Theory of Romantic Attachment in Adulthood03:34

Theory of Romantic Attachment in Adulthood

Attachment is a long-standing connection or bond with others. While Attachment Theory was conceived in developmental psychology to describe infant-caregiver bonding, it's been extended into adulthood to include romantic relationships.

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Related Experiment Video

Updated: May 21, 2026

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

Functional network dysfunction in anxiety and anxiety disorders.

C M Sylvester1, M Corbetta, M E Raichle

  • 1Department of Psychiatry, Washington University, Saint Louis, MO, USA. sylvestc@psychiatry.wustl.edu

Trends in Neurosciences
|June 5, 2012
PubMed
Summary
This summary is machine-generated.

Anxiety disorders are linked to altered brain functional networks. This study identifies specific network dysfunctions, offering new diagnostic and treatment targets for anxiety.

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Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety
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Last Updated: May 21, 2026

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

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Published on: July 1, 2014

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety
04:20

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety

Published on: November 11, 2022

Area of Science:

  • Systems neuroscience
  • Cognitive neuroscience
  • Neuroimaging

Background:

  • The human brain is organized into functional networks, each supporting distinct cognitive processes.
  • Understanding network dysfunction is crucial for diagnosing and treating psychiatric disorders.
  • Anxiety disorders represent a significant public health challenge with complex neural underpinnings.

Purpose of the Study:

  • To investigate the functional network patterns associated with anxiety disorders and high trait anxiety.
  • To propose a functional network model for anxiety pathology.
  • To explore the potential of this model in differentiating anxiety from other psychiatric conditions and guiding treatment.

Main Methods:

  • Utilizing neuroimaging techniques to analyze brain activity during rest and cognitive tasks.
  • Examining functional connectivity within and between brain networks.
  • Comparing network activity patterns in individuals with anxiety disorders versus healthy controls.

Main Results:

  • Identified increased functioning in the cingulo-opercular and ventral attention networks in anxiety.
  • Observed decreased functioning in the fronto-parietal and default mode networks in anxiety.
  • Demonstrated a distinct functional network signature for anxiety disorders.

Conclusions:

  • Anxiety disorders exhibit a specific pattern of functional brain network dysfunction.
  • This functional network model may aid in differentiating anxiety from major depression.
  • The identified network alterations provide potential targets for novel anxiety treatments.