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Updated: May 21, 2026

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Studying Cavitation Enhanced Therapy
Published on: April 9, 2021
Study of PET Detector Performance with Varying SiPM Parameters and Readout Schemes.
Xiaoli Li1, Cate Lockhart, Tom K Lewellen
1University of Washington Department of Physics, Seattle, WA USA (phone: 206-543-0629; fax: 206-543-8356; lixioli@u.washington.edu ).
Summary
This study evaluates monolithic crystal PET detectors using silicon photomultiplier arrays. Detector performance is optimized by managing photon detection efficiency and gain shifts, with cooling planned to reduce noise.
Area of Science:
- Medical Imaging
- Detector Physics
- Nuclear Instrumentation
Background:
- Monolithic crystal Positron Emission Tomography (PET) detectors offer improved performance.
- Sensor on the Entrance Surface (SES) design requires advanced readout strategies.
- Silicon Photomultiplier (SiPM) arrays are crucial for high-resolution PET imaging.
Purpose of the Study:
- To characterize the spatial resolution of a monolithic crystal PET detector with a 2D SiPM array.
- To investigate the impact of various SiPM parameters and readout schemes on detector performance.
- To identify optimal parameters for a practical PET detector design.
Main Methods:
- Simulated a 49.2mm x 49.2mm x 15mm LYSO crystal PET detector using a 12x12 SiPM array.
- Employed a statistics-based positioning (SBP) method for event positioning and depth of interaction (DOI) decoding.
- Analyzed the effects of photon detection efficiency (PDE), gain variability, instability, and dark count noise on spatial resolution.
Main Results:
- Individual channel readout yielded better spatial resolution than row-column summing.
- PDE and gain shifts between testing and calibration significantly degraded spatial resolution and introduced positioning bias.
- Dark count noise impacted intrinsic spatial resolution.
- No data normalization is needed for PDE variability up to 12% FWHM and gain variability up to 15% FWHM.
Conclusions:
- A row-column summing readout scheme without data normalization is proposed for efficiency.
- Cooling detectors below room temperature will reduce dark count noise.
- Active temperature control of SiPMs will minimize PDE and gain drifts, enhancing detector stability and performance.

