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Updated: May 20, 2026

Isolation, Characterization and MicroRNA-based Genetic Modification of Human Dental Follicle Stem Cells
Published on: November 16, 2018
Stem cell and biomaterials research in dental tissue engineering and regeneration
Orapin V Horst1, Miquella G Chavez, Andrew H Jheon
1Division of Endodontics, Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, USA.
Abstract:
This review summarizes approaches used in tissue engineering and regenerative medicine, with a focus on dental applications. Dental caries and periodontal disease are the most common diseases resulting in tissue loss. To replace or regenerate new tissues, various sources of stem cells have been identified such as somatic stem cells from teeth and peridontium. Advances in biomaterial sciences including microfabrication, self-assembled biomimetic peptides, and 3-dimensional printing hold great promise for whole-organ or partial tissue regeneration to replace teeth and periodontium.
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