Related Experiment Video
Updated: May 19, 2026
07:43
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Pituicytoma: Report of two cases
Zhigang Mao1, Weiwei Xiao, Haijun Wang
1Department of Neurosurgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.
Oncology Letters
|August 8, 2012
Summary
Pituicytoma, a rare pituitary tumor, presents with visual issues and diabetes insipidus. Surgical resection is the primary treatment, offering a viable option for managing this condition.
Area of Science:
- Neuro-oncology
- Endocrinology
- Pathology
Background:
- Pituicytomas are rare tumors arising from the pituitary stalk or gland.
- They can present with diverse symptoms including visual disturbances and hormonal imbalances.
Purpose of the Study:
- To describe the clinical, imaging, and histopathological features of two pituicytoma cases.
- To discuss the differential diagnosis and optimal management of pituicytoma.
Main Methods:
- Case report analysis of two female patients with pituicytoma.
- Review of clinical presentation, imaging characteristics (MRI), and histopathological findings (H&E, immunohistochemistry).
Main Results:
- Both patients presented with visual complaints, diabetes insipidus, headaches, and menstrual disorders.
- Imaging revealed intrasellar/suprasellar masses with homogeneous enhancement; one originated from the pituitary stalk.
- Histopathology showed spindle cells with strong S-100, vimentin, and EMA expression; GFAP was focally positive.
Conclusions:
- Pituicytoma, potentially originating from the pituitary stalk, requires differentiation from other pituitary stalk masses.
- Surgical resection is the preferred initial treatment, with moderate bleeding observed during procedures.